111 Biopharmaceutics (3.5 units) Winter
Instructor(s): X. Chen Prerequisite(s): First-year standing in School of Pharmacy.
Restrictions: None Activities: Lecture, Conference
This course is meant to introduce students to basic pharmacokinetic and biopharmaceutic principles. Pharmacokinetic concepts will first be introduced, including the concepts of clearance and volume of distribution as they relate to drug concentration-time relationships for common routes of administration. The second half of the course will focus on biopharmaceutics -- how drugs get to the site of absorption, drug dissolution, membrane permeability, bioavailability and bioequivalence.
112 Biostatistics (2 units) Winter
Instructor(s): J. Lightwood Prerequisite(s): none
Restrictions: none Activities: Lecture
This course is an introductory course in biostatistics covering topics such as elementary probability theory, hypothesis testing, analysis of variance, t-tests, chi-square tests, regression and correlation, nonparametric methods, estimation and confidence intervals.
113 Drug Delivery: From Biologics to Devices (3 units) Spring
Instructor(s): T. Desai, P. Babbitt, T. Kortemme, F. Szoka, S. Roy Prerequisite(s): BIOPHRM SC 111
Restrictions: First year PharmD students. Activities: Lecture
This course will introduce pharmacy students to the principles of protein structure relevant to developing them as drugs and drug targets. They will also learn about the various routes and delivery systems for administration of drugs. Additionally, they will gain exposure into the imaging modalities used for evaluating these drugs, and the role of medical devices in enhancing therapy.
115 Genetics and Pharmacogenetics (2.5 units) Spring
Instructor(s): S. Guo, D. Kroetz, E. Burchard Prerequisite(s): Concurrent enrollment in BPS 113 or permission of instructor
Restrictions: None. Activities: Lecture, Workshop
This is a course to introduce pharmacy students to the basic principles of genetics and apply them to pharmacogenetics.
121 Pharmacokinetic Variability (3.5 units) Fall
Instructor(s): D. Kroetz Prerequisite(s): Biopharmaceutical Sciences 111 and 113.
Restrictions: none Activities: Lecture, Workshop
This course is meant to introduce the second year students to the primary determinants of pharmacokinetic variability, including 1) the influence of pharmacogenomics as well as induction and inhibition of drug metabolism and transport on variability in drug clearance and bioavailability, and 2) physiologic determinants of variability including age, body composition, renal and hepatic disease.
133 Pharmacokinetics in Drug Development (3 units) Spring
Instructor(s): F. Aweeka Prerequisite(s): Satisfactory completion of BPS 122.
Activities: Lecture, Project
The course will provide advanced training in pharmacokinetics with a focus on the issues involved with drug development.
134 Research Design & Statistics in Drug Development (3 units) Winter
Instructor(s): N. Sambol Prerequisite(s): None.
Restrictions: This course is required for students in the Pharmaceutical Sciences Pathway, but is open to all students as an elective if space permits. Activities: Lecture, Project
This course covers detailed aspects of optimizing research design for clinical and basic research. The material presented builds on the content covered in the Study Design Course of the first year curriculum. Design strategies for varying types of research as well as skills for critical evaluation of research studies and literature will be the primary focus. In addition, the ethics of using animals and humans will be discussed.
135 Principles of Pharmacogenomics (3 units) Spring
Instructor(s): N. Ahituv Prerequisite(s): None.
Restrictions: None. Activities: Lecture, Conference
This course provides students with a comprehensive overview of the genetic basis for differences in drug response. Genetic variability in drug receptors, transporters and enzymes as well as regulatory proteins involved in promoting and inhibiting transcription and translation will be discussed. The course also covers toxicogenetics and an introduction to computational genomics.
171 Precision & Personalized Medicine: Healthcare Frontiers (1 units) Spring
Instructor(s): E. Burchard Prerequisite(s): None
Restrictions: None. The course is open to professional students from all programs as well as graduate students. Activities: Lecture
Precision and Personalized Medicine offer great potential to improve biomedical research and patient care. Through this elective, students will learn about the principles of precision and personalized medicine and the current advancements in each area. Students will also engage in dialog with thought-leaders in these fields, and discuss potential solutions to obstacles these fields are facing. These experiences will prepare students to be pioneers in research and healthcare for years to come.
198 Supervised Study in Biopharmaceutical Sciences (1 - 5 units) Fall, Winter, Spring
Instructor(s): Staff
Activities: Seminar, Laboratory
Library research and directed reading under supervision of a member of the faculty with the approval of the chairperson of the department.
272A Adv Drug Delivery: Controlled and Targeted Drug Delivery (2 units) Winter
Instructor(s): F. Szoka Prerequisite(s): Chemistry 241 or equivalent.
Activities: Laboratory, Project
The focus of this course is on the chemical, biophysical and biological factors that impact on targeted and controlled drug delivery systems. There is a particular emphasis on colloidal systems and systems that provide a regulated controlled release.