133  Pharmacokinetics in Drug Development  (3 units)   Spring

Instructor(s): F. Aweeka       Prerequisite(s): Satisfactory completion of BPS 122.

Restrictions: None.       Activities: Direct - Lecture, Direct - Project, Student - Lecture

The course will provide advanced training in pharmacokinetics with a focus on the issues involved with drug development.

134  Research Design & Statistics in Drug Development  (3 units)   Winter

Course will not be offered in: Winter 2022

Instructor(s): N. Sambol       Prerequisite(s): None.

Restrictions: This course is required for students in the Pharmaceutical Sciences Pathway, but is open to all students as an elective if space permits.       Activities: Direct - Lecture, Direct - Project, Student - Lecture

This course covers detailed aspects of optimizing research design for clinical and basic research. The material presented builds on the content covered in the Study Design Course of the first year curriculum. Design strategies for varying types of research as well as skills for critical evaluation of research studies and literature will be the primary focus. In addition, the ethics of using animals and humans will be discussed.

135  Principles of Pharmacogenomics  (3 units)   Spring

Instructor(s): N. Ahituv       Prerequisite(s): None.

Restrictions: None.       Activities: Direct - Lecture, Direct - Conference, Student - Lecture, Student - Conference

This course provides students with a comprehensive overview of the genetic basis for differences in drug response. Genetic variability in drug receptors, transporters and enzymes as well as regulatory proteins involved in promoting and inhibiting transcription and translation will be discussed. The course also covers toxicogenetics and an introduction to computational genomics.