204A Macromolecular Structure and Interactions (4 units) Fall
Restrictions: First year Biophysics and CCB students Activities: Direct - Lecture, Direct - Lab-Skills, Direct - Lab-Science, Direct - Project, Direct - Discussion, Student - Lecture, Student - Project
In this course, we will pursue a qualitative & quantitative understanding of the physical basis of macromolecular function. We will examine: the nature & quantification of the forces that drive macromolecular interactions, both intramolecular (macromolecular folding), & with other proteins and ligands; diffusion & active transport of macromolecules; the structural underpinnings of the kinetics & thermodynamics of macromolecular reactions; & the physical basis of important biophysical methods.
204B Methods in Macromolecular Structure (4 units) Winter
Restrictions: None Activities: Direct - Lecture, Direct - Lab-Skills, Direct - Lab-Science, Direct - Project, Direct - Field Work, Direct - Discussion, Student - Lecture, Student - Project
This is a team-based class where students work in small groups develop their own analysis of real data that they have collected. Statistical aspects of rigor and reproducibility in structural biology will be emphasized throughout lectures, journal club presentations, and hands-on activities.
205B Complex Biological Systems B (2.5 - 4 units) Winter
Restrictions: None Activities: Direct - Lecture, Direct - Lab-Skills, Direct - Lab-Science, Direct - Project, Student - Lecture
This course will teach the fundamentals of dissecting and understanding complex biological systems using didactic instruction in addition to practical lab experience in the context of a team based project. For each project, students will learn and use modern genomic and proteomic tools to characterize transcriptional circuits within a model organism. This course is a continuation of material introduced in 205A.
210 Biological Light Microscopy (4 units) Spring
Instructor(s): O. Weiner Prerequisite(s): None
Restrictions: No first year students. Laboratory space is limited to 24 students; instructor permission required. Activities: Direct - Lecture, Direct - Lab-Skills, Student - Lecture
This course provides a comprehensive introduction to light microscopy as it is commonly used for imaging biological samples. No previous experience with microscopy is assumed; the course begins with basic optics and covers the design and operation of modern research microscopes. Advanced techniques including confocal microscopy, TIRF, and super-resolution techniques are covered. This course includes both labs and lectures.
215 Laboratory Rotation (1 - 8 units) Fall, Winter, Spring, Summer
Instructor(s): Staff Prerequisite(s): None
Restrictions: None Activities: Laboratory
An introduction to the specific research currently underway within a faculty member's laboratory.
219 Special Topics in Biophysics (3 units) Fall, Spring
Instructor(s): Staff Prerequisite(s): None.
Restrictions: First-year graduate students; other graduate and professional students with permission of instructor. Activities: Direct - Lecture, Direct - Independent Study, Direct - Conference, Student - Lecture
Each course offering will focus on the literature of a current important area of Biophysics. Students will be expected to read assigned papers critically before class and to present and discuss papers in class. Students will also be expected to write and present a brief research proposal based upon their reading. Topics in Molecular, Cellular, Developmental Systems and Computational Biology will be covered in individual courses.
220 Biophysics Seminar (1 units) Fall, Winter, Spring
Instructor(s): A. Frankel Prerequisite(s): None.
Restrictions: n/a Activities: Direct - Lecture, Student - Lecture
This course consists of presentation and discussion of research in quantitative biology and biophysics by outside speakers.
223 Scientific Communication Seminar (1 units) Fall, Winter, Spring
Instructor(s): T. Kortemme Prerequisite(s): None
Restrictions: None Activities: Direct - Seminar, Student - Seminar
This seminar will provide graduate students with a forum in which to develop seminar and poster presentation skills; critically organize and critically review scientific data; and analyze and question oral scientific presentations.
224 Critical Topics in Biophysics (1 units) Fall, Winter, Spring
Restrictions: None Activities: Direct - Lecture, Student - Lecture
Critical review of published scientific papers from scholarly journals, including comprehension, analysis and evaluation of published scientific data.
241 Physical Biology (5 units) Fall
Instructor(s): M. Grabe Prerequisite(s): none
Restrictions: none Activities: Direct - Lecture, Student - Lecture
This is a course on molecular thermodynamics and statistical mechanics. It covers the concepts of entropy, enthalpy, heat capacity, free energy, ligand binding, solvation, the properties of water, the hydrophobic effect, solution electrostatics, adsorption, and physical and chemical kinetics.
250 Research (1 - 8 units) Fall, Winter, Spring, Summer
Instructor(s): Staff Prerequisite(s): BIOPHYSICS 204A, BIOPHYSICS 204B
Restrictions: NA Activities: Conference, Project
In this course, students will work together with a primary research advisor to select a research question and design a project workplan that will be carried out by the student. Through this activity, the student will gain experience in research strategy, learn techniques associated with modern biomedical research and practice how to interpret results. At the conclusion of the course, the student will present on their progress.
297 Scientific writing: applying for the NSF predoctoral fellows (1 units) Fall
Instructor(s): Z. Gartner Prerequisite(s): None
Restrictions: None Activities: Direct - Seminar, Direct - Workshop, Student - Seminar, Student - Workshop
Communicating your best ideas is critical to obtaining the resources necessary to work on them. This course prepares you to conceive, organize, and communicate scientific ideas in written form. Built around the NSF GRF application, this course covers important funding agencies and fellowship opportunities, formulating a research plan in the form of hypotheses and specific aims, organizing research proposals,and peer editing. Course culminates in submission of materials to NSF and other agencies
299 Dissertation (0 units) Fall, Winter, Spring, Summer
Instructor(s): Staff Prerequisite(s): Advancement to candidacy and permission of the graduate adviser
Restrictions: Graduate students after advancement to candidacy
For graduate students engaged in writing the dissertation for the PhD degree.