202 Microbial Pathogenesis (3 units) Fall
Instructor(s): J. Engel Prerequisite(s): College course in microbiology recommended.
Restrictions: None Activities: Lecture
The goal of the course is to provide a comprehensive understanding of the molecular mechanisms of microbial pathogenesis in the 21st century. Over the 10 week period, students will learn by a combination of concise lectures provided by the faculty in conjunction with student-led discussion of 1-2 relevant papers for most sessions. Key aspects of bacterial, fungal, and parasite pathogenesis, as well as innate immunity, are covered. Cross-listed with Cell Bio 202.
204 Molecular and Cellular Immunology (3 units) Fall
Instructor(s): J. Cyster, C. Lowell Prerequisite(s): Undergraduate level knowledge of molecular biology, cell biology and genetics. Some basic knowledge of the immune system is helpful but not required.
Restrictions: None other than the prerequisite Activities: Direct - Lecture, Direct - Workshop, Direct - Discussion, Student - Lecture, Student - Discussion
Topics to be covered: Mechanisms of innate immunity, inflammation, immunoglobulin gene rearrangements, cell biology of antigen presentation to T-cells and of lymphocyte trafficking, antigen and cytokine receptor structure and signaling, lymphocyte development and activation, mechanisms of cell-mediated killing of infected and neoplastic cells, whole organism immune response to infection, diseases of the immune system, including allergy, autoimmunity, and AIDS, and immune cell engineering.
212 Immunology Journal Club (1 units) Fall, Winter, Spring
Instructor(s): A. Erlebacher Prerequisite(s): Micro 204
Restrictions: None. Activities: Direct - Lecture, Student - Lecture
Course explores recent discoveries in Immunology. Students required to present once for 25 minutes. Presentations can be on recent publications of immunological interest, or student's own research. The focus on current immunological knowledge and recent breakthroughs exposes students to material relevant to their research projects. Faculty are assigned for each presentation as necessary. All students in ImmunoX-affiliated labs are required to take the course.